Creatine vs Beta-Alanine: Which Is Right for You?
Creatine boosts explosive power; beta-alanine fights muscular fatigue. But combining them may be the real performance unlock — here's the science behind it.
How Creatine Works
Creatine phosphate is the primary fuel for ATP regeneration during maximal-intensity efforts lasting 1–10 seconds. By saturating your muscles with creatine (loading: 20 g/day for 5 days, then 3–5 g/day maintenance), you extend the phosphocreatine window by roughly 10–15%. The practical outcome: 1–2 extra reps on heavy compound lifts, a measurable improvement in sprint times, and faster recovery between sets. Meta-analyses consistently show creatine monohydrate produces 5–15% strength gains over 4–12 week protocols.
How Beta-Alanine Works
Beta-alanine is a rate-limiting precursor to carnosine — a dipeptide that buffers hydrogen ions (H+) in muscle tissue. During high-rep sets or endurance intervals, H+ accumulation causes the burning sensation that forces you to stop. More carnosine = higher buffering capacity = more reps before failure. Effective dose: 3.2–6.4 g/day. The well-known paresthesia (skin tingling) is harmless and fades with consistent use or by splitting doses throughout the day.
When to Use Creatine vs Beta-Alanine
Creatine dominates for power sports: powerlifting, sprinting, Olympic lifting, team sports with repeated sprints. Beta-alanine excels in the 1–4 minute effort zone: 400 m–1500 m running, CrossFit WODs, high-rep bodybuilding sets (12–20 reps). If your sport involves both short explosive efforts AND prolonged high-intensity intervals — football, rugby, MMA — stacking both makes clear sense.
The Stack: Why Combining Both Is Effective
Creatine and beta-alanine target completely different fatigue mechanisms, making them fully complementary with no interaction or competition for uptake. A 10-week randomised controlled trial published in the International Journal of Sport Nutrition found that the creatine + beta-alanine group gained significantly more lean mass and lost more body fat than either supplement alone. Load creatine for the first 5 days, then maintain both at standard doses indefinitely.
Practical Protocol
Loading phase (days 1–5): Creatine monohydrate 5 g × 4 times daily. Beta-alanine 1.6 g × 4 times daily (minimises tingling). Maintenance (ongoing): Creatine 3–5 g/day, any time. Beta-alanine 3.2–6.4 g/day split. Take both with carbohydrates to enhance muscle uptake. Both supplements are effective regardless of training day or rest day — consistency of daily intake matters more than timing.
Written by
Ivan Kowalski
Exercise Physiologist